1. INTRODUCTION
Fumonisins (FBs), including fumonisin B1 (FB1) and fumonisin B2 (FB2), are known to reduce animal performance and feed efficiency, increase mortality and impair the immune system in animals.
In broiler chickens, the FBs can adversely affect feed intake and weight gain, as well as liver and kidney relative weights. In addition, indirect effects such as oxidative stress have been observed during intoxication.
The aim of this study was to evaluate the efficacy of an anti-mycotoxins agent (AMA) through:
1) the determination of biomarkers of exposure to fumonisins (sphinganine/sphingosine ratio, SA/SO);
2) the assessment of the serum biochemistry and the determination of oxidative stress markers;
3) the mitigation of liver damage in broiler chickens challenged by FB1 and FB2.
2. MATERIAL AND METHODS
RESULTS
3. CONCLUSIONS
The anti-mycotoxins agent showed high efficacy on the biomarkers of exposure to FBs. Furthermore, the product showed to be effective in alleviating the oxidative stress and counteracting the liver damage. This highlights the potential of the anti mycotoxins agent to protect the health and performance in broilers chickens exposed to FBs.
