1. INTRODUCTION
Different molecular mechanisms are involved in mycotoxin induced toxicity.
Oxidative stress and subsequent free radical generation play a pivotal role in human and animal health. Indeed, an alteration in the balance between free radicals and antioxidant defense systems can induce chemical damage to DNA, proteins and lipids, as observed after exposure to mycotoxins (Assi, 2007).
Since exposure to mycotoxins is difficult to avoid, dietary strategies have been developed to mitigate the damage caused by mycotoxins (Li et al.,2005).
Several studies have demonstrated the effectiveness of compounds with antioxidant activity in alleviating the effects of oxidative stress caused by mycotoxins. In this respect, the inclusion of natural antioxidants has shown the ability to reduce or prevent the secondary effects of mycotoxin (Wang et al., 2023).
AIM: To analyze the in vitro antioxidant capacity in immortalized human carcinoma cells (Caco-2) of a product formulated from natural compounds with a potential to reduce the oxidative stress.
2. MATERIALS AND METHODS
3. MATERIALS AND METHODS
4. CONCLUSIONS
The product demonstrated non-cytotoxic effects and significantly enhanced cell viability, indicating potential growth stimulation in the GI tract.
Moreover, the multi-action complex showed a notable reduction in ROS levels, highlighting its broad-spectrum free radical scavenging activity.
These findings highlight the importance of include natural antioxidants in animal diet to mitigate the harmful effects of mycotoxin-induced oxidative stress, and provide a basis for further research and potential applications to target related health problems.
